3vh0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:21, 8 November 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3vh0.png|left|200px]]
 
-
<!--
+
==Crystal structure of E. coli YncE complexed with DNA==
-
The line below this paragraph, containing "STRUCTURE_3vh0", creates the "Structure Box" on the page.
+
<StructureSection load='3vh0' size='340' side='right'caption='[[3vh0]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3vh0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VH0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vh0 OCA], [https://pdbe.org/3vh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vh0 RCSB], [https://www.ebi.ac.uk/pdbsum/3vh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vh0 ProSAT]</span></td></tr>
-
{{STRUCTURE_3vh0| PDB=3vh0 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/YNCE_ECOLI YNCE_ECOLI]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
beta-Propellers are widely utilized in nature as recognition modules. The well conserved beta-propeller fold exhibits a high degree of functional diversity, which is probably accomplished through variations in the surface properties of the proteins. Little is known about the interactions between beta-propeller proteins and nucleic acids. In the present study, it has been found that the bacterial beta-propeller protein YncE binds to DNA. Crystal structures of YncE in the free form and complexed with DNA revealed that the surface region of YncE corresponding to the `canonical' substrate-binding site forms essential contacts with DNA. A single DNA base within a single-stranded DNA region is trapped in the hydrophobic pocket located within the central channel of the beta-propeller protein. These data provide physical evidence for the DNA-binding ability of the previously uncharacterized YncE and also suggest that the `canonical' substrate-binding site may be commonly adapted to facilitate nucleic acid binding in a subset of beta-propeller proteins.
-
===Crystal structure of E. coli YncE complexed with DNA===
+
Structural basis for the DNA-binding activity of the bacterial beta-propeller protein YncE.,Kagawa W, Sagawa T, Niki H, Kurumizaka H Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1045-53. Epub 2011, Nov 5. PMID:22120742<ref>PMID:22120742</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_22120742}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 3vh0" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 22120742 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_22120742}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Escherichia coli K-12]]
-
[[3vh0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VH0 OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Kagawa W]]
-
==Reference==
+
[[Category: Kurumizaka H]]
-
<ref group="xtra">PMID:022120742</ref><references group="xtra"/>
+
[[Category: Niki H]]
-
[[Category: Escherichia coli]]
+
[[Category: Sagawa T]]
-
[[Category: Kagawa, W.]]
+
-
[[Category: Kurumizaka, H.]]
+
-
[[Category: Niki, H.]]
+
-
[[Category: Sagawa, T.]]
+
-
[[Category: Beta-propeller]]
+
-
[[Category: Protein binding-dna complex]]
+

Current revision

Crystal structure of E. coli YncE complexed with DNA

PDB ID 3vh0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3vh0"
Personal tools