This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2km1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2km1" [edit=sysop:move=sysop])
Current revision (06:46, 1 May 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2km1.png|left|200px]]
 
-
<!--
+
==Solution structure of the N-terminal domain of the yeast protein Dre2==
-
The line below this paragraph, containing "STRUCTURE_2km1", creates the "Structure Box" on the page.
+
<StructureSection load='2km1' size='340' side='right'caption='[[2km1]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2km1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KM1 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2km1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2km1 OCA], [https://pdbe.org/2km1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2km1 RCSB], [https://www.ebi.ac.uk/pdbsum/2km1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2km1 ProSAT]</span></td></tr>
-
{{STRUCTURE_2km1| PDB=2km1 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Solution structure of the N-terminal domain of the yeast protein Dre2===
+
[https://www.uniprot.org/uniprot/DRE2_YEAST DRE2_YEAST] Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein TAH18. Has anti-apoptotic effects in the cell. Involved in negative control of H(2)O(2)-induced cell death.[HAMAP-Rule:MF_03115]<ref>PMID:12759774</ref> <ref>PMID:18625724</ref> <ref>PMID:19194512</ref> <ref>PMID:20802492</ref> <ref>PMID:21902732</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
[[2km1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KM1 OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2km1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2km1 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Baldacci, G.]]
+
[[Category: Baldacci G]]
-
[[Category: Craescu, C T.]]
+
[[Category: Craescu CT]]
-
[[Category: Delagoutte, E.]]
+
[[Category: Delagoutte E]]
-
[[Category: Soler, N.]]
+
[[Category: Soler N]]
-
[[Category: Vernis-Beringue, L.]]
+
[[Category: Vernis-Beringue L]]
-
[[Category: Antiapoptotic]]
+
-
[[Category: Dre2]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Yeast]]
+

Current revision

Solution structure of the N-terminal domain of the yeast protein Dre2

PDB ID 2km1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2km1"
Personal tools