2l74

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[[Image:2l74.png|left|200px]]
 
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==Solution structure of the PilZ domain protein PA4608 complex with c-di-GMP identifies charge clustering as molecular readout==
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The line below this paragraph, containing "STRUCTURE_2l74", creates the "Structure Box" on the page.
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<StructureSection load='2l74' size='340' side='right'caption='[[2l74]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2l74]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L74 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2E:9,9-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d 3,2-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)'>C2E</scene></td></tr>
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{{STRUCTURE_2l74| PDB=2l74 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l74 OCA], [https://pdbe.org/2l74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l74 RCSB], [https://www.ebi.ac.uk/pdbsum/2l74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l74 ProSAT]</span></td></tr>
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</table>
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===Solution structure of the PilZ domain protein PA4608 complex with c-di-GMP identifies charge clustering as molecular readout===
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== Function ==
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[https://www.uniprot.org/uniprot/CDGBP_PSEAE CDGBP_PSEAE] Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.<ref>PMID:17096419</ref> <ref>PMID:21280119</ref> <ref>PMID:21310957</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21310957 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21310957}}
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==About this Structure==
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[[2l74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L74 OCA].
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==Reference==
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<ref group="xtra">PMID:021310957</ref><references group="xtra"/>
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Allan, M.]]
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[[Category: Allan M]]
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[[Category: Grzesiek, S.]]
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[[Category: Grzesiek S]]
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[[Category: Habazettl, J.]]
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[[Category: Habazettl J]]
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[[Category: Jenal, U.]]
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[[Category: Jenal U]]
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[[Category: C-di-gmp]]
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[[Category: C-di-gmp binding protein]]
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[[Category: Pa4608]]
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[[Category: Pilz]]
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[[Category: Unknown function]]
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Current revision

Solution structure of the PilZ domain protein PA4608 complex with c-di-GMP identifies charge clustering as molecular readout

PDB ID 2l74

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