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2l93

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[[Image:2l93.png|left|200px]]
 
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==Solution structure of the C-terminal domain of Salmonella H-NS==
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The line below this paragraph, containing "STRUCTURE_2l93", creates the "Structure Box" on the page.
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<StructureSection load='2l93' size='340' side='right'caption='[[2l93]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2l93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L93 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l93 OCA], [https://pdbe.org/2l93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l93 RCSB], [https://www.ebi.ac.uk/pdbsum/2l93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l93 ProSAT]</span></td></tr>
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{{STRUCTURE_2l93| PDB=2l93 | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the C-terminal domain of Salmonella H-NS===
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[https://www.uniprot.org/uniprot/HNS_SALTY HNS_SALTY] H-NS binds tightly to ds-DNA, increases its thermal stability and inhibits transcription. It also binds to ss-DNA and RNA but with a much lower affinity. H-NS has possible histone-like function. May be a global transcriptional regulator through its ability to bind to curved DNA sequences, which are found in regions upstream of a certain subset of promoters. It plays a role in the thermal control of pili production. It is subject to transcriptional auto-repression. It binds preferentially to the upstream region of its own gene recognizing two segments of DNA on both sides of a bend centered around -150 (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_21673140}}, adds the Publication Abstract to the page
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21673140 is the PubMed ID number.
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[[Category: Li Y]]
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{{ABSTRACT_PUBMED_21673140}}
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==About this Structure==
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[[2l93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L93 OCA].
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==Reference==
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<ref group="xtra">PMID:021673140</ref><references group="xtra"/>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Li, Y.]]
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[[Category: At hook]]
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[[Category: Dna binding protein]]
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[[Category: H-n]]
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Current revision

Solution structure of the C-terminal domain of Salmonella H-NS

PDB ID 2l93

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