1m06
From Proteopedia
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- | [[Image:1m06.png|left|200px]] | ||
- | + | ==Structural Studies of Bacteriophage alpha3 Assembly, X-Ray Crystallography== | |
- | + | <StructureSection load='1m06' size='340' side='right'caption='[[1m06]], [[Resolution|resolution]] 3.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1m06]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_alpha3 Escherichia phage alpha3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M06 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m06 OCA], [https://pdbe.org/1m06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m06 RCSB], [https://www.ebi.ac.uk/pdbsum/1m06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m06 ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/CAPSD_BPAL3 CAPSD_BPAL3] Assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins F. Upon virus binding to host cell, one of the spikes dissociates from the capsid and the virus interacts with LPS through the exposed EF loops on the F proteins. After the genome had been ejected, the channel formed by the F proteins at the unique fivefold axis remains open.[UniProtKB:P03641] | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m0/1m06_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | [[1m06]] is a 4 chain structure with sequence from [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m06 ConSurf]. |
- | + | <div style="clear:both"></div> | |
- | + | __TOC__ | |
- | < | + | </StructureSection> |
- | [[ | + | [[Category: Escherichia phage alpha3]] |
- | [ | + | [[Category: Large Structures]] |
- | [ | + | [[Category: Baker TS]] |
- | [ | + | [[Category: Bernal RA]] |
- | [ | + | [[Category: Bowman V]] |
- | [[ | + | [[Category: Chipman PR]] |
- | [ | + | [[Category: Fane BA]] |
- | [[ | + | [[Category: Hafenstein S]] |
- | [[Category: | + | [[Category: Olson NH]] |
- | [[Category: | + | [[Category: Rossmann MG]] |
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Current revision
Structural Studies of Bacteriophage alpha3 Assembly, X-Ray Crystallography
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