3uvv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid== | |
| + | <StructureSection load='3uvv' size='340' side='right'caption='[[3uvv]], [[Resolution|resolution]] 2.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uvv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UVV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9CR:(9CIS)-RETINOIC+ACID'>9CR</scene>, <scene name='pdbligand=T3:3,5,3TRIIODOTHYRONINE'>T3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvv OCA], [https://pdbe.org/3uvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uvv RCSB], [https://www.ebi.ac.uk/pdbsum/3uvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THA_CHICK THA_CHICK] Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. | ||
| - | + | ==See Also== | |
| - | + | *[[Retinoid X receptor 3D structures|Retinoid X receptor 3D structures]] | |
| - | + | *[[Thyroid hormone receptor 3D structures|Thyroid hormone receptor 3D structures]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brunzelle JS]] | ||
| + | [[Category: Fernandez EJ]] | ||
| + | [[Category: Putcha B-DK]] | ||
| + | [[Category: Wright E]] | ||
Current revision
Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid
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