3v71

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'''Unreleased structure'''
 
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The entry 3v71 is ON HOLD until Paper Publication
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==Crystal structure of PUF-6 in complex with 5BE13 RNA==
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<StructureSection load='3v71' size='340' side='right'caption='[[3v71]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Qiu, C., Kershner, A., Wang, Y., Holley, C.H., Wilinski, D., Keles, S., Kimble, J., Wickens, M., Hall, T.M.T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V71 FirstGlance]. <br>
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Description: Crystal structure of PUF-6 in complex with 5BE13 RNA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [https://pdbe.org/3v71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [https://www.ebi.ac.uk/pdbsum/3v71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v71 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUF7_CAEEL PUF7_CAEEL] RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.<ref>PMID:17234175</ref> <ref>PMID:22205700</ref> <ref>PMID:22542599</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Caenorhabditis elegans]]
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[[Category: Large Structures]]
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[[Category: Hall TMT]]
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[[Category: Holley CH]]
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[[Category: Keles S]]
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[[Category: Kershner A]]
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[[Category: Kimble J]]
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[[Category: Qiu C]]
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[[Category: Wang Y]]
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[[Category: Wickens M]]
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[[Category: Wilinski D]]

Current revision

Crystal structure of PUF-6 in complex with 5BE13 RNA

PDB ID 3v71

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