3v74

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'''Unreleased structure'''
 
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The entry 3v74 is ON HOLD until Paper Publication
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==crystal structure of FBF-2 in complex with gld-1 FBEa13 RNA==
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<StructureSection load='3v74' size='340' side='right'caption='[[3v74]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Wang, Y., Qiu, C., Kershner, A., Holley, C.P., Wilinski, D., Keles, S., Kimble, J., Wickens, M., Hall, T.M.T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3v74]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V74 FirstGlance]. <br>
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Description: crystal structure of FBF-2 in complex with gld-1 FBEa13 RNA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v74 OCA], [https://pdbe.org/3v74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v74 RCSB], [https://www.ebi.ac.uk/pdbsum/3v74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v74 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Caenorhabditis elegans]]
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[[Category: Large Structures]]
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[[Category: Hall TMT]]
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[[Category: Holley CP]]
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[[Category: Keles S]]
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[[Category: Kershner A]]
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[[Category: Kimble J]]
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[[Category: Qiu C]]
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[[Category: Wang Y]]
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[[Category: Wickens M]]
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[[Category: Wilinski D]]

Current revision

crystal structure of FBF-2 in complex with gld-1 FBEa13 RNA

PDB ID 3v74

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