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3tux

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[[Image:3tux.jpg|left|200px]]
 
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==Crystal structure of RtcA.ATP.Mn ternary complex==
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The line below this paragraph, containing "STRUCTURE_3tux", creates the "Structure Box" on the page.
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<StructureSection load='3tux' size='340' side='right'caption='[[3tux]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tux]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TUX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3tux| PDB=3tux | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tux OCA], [https://pdbe.org/3tux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tux RCSB], [https://www.ebi.ac.uk/pdbsum/3tux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tux ProSAT]</span></td></tr>
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</table>
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===Crystal structure of RtcA.ATP.Mn ternary complex===
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== Function ==
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[https://www.uniprot.org/uniprot/RTCA_ECOLI RTCA_ECOLI] Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.<ref>PMID:9738023</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22167800 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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{{ABSTRACT_PUBMED_22167800}}
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[[Category: Large Structures]]
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[[Category: Chakravarty AK]]
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==About this Structure==
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[[Category: Shuman S]]
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[[3tux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUX OCA].
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[[Category: Smith P]]
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==Reference==
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<ref group="xtra">PMID:022167800</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
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[[Category: RNA-3'-phosphate cyclase]]
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[[Category: Chakravarty, A K.]]
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[[Category: Shuman, S.]]
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[[Category: Smith, P.]]
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[[Category: Cyclase family]]
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[[Category: Cyclization of rna 3'-phosphate end]]
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[[Category: Transferase]]
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Current revision

Crystal structure of RtcA.ATP.Mn ternary complex

PDB ID 3tux

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