This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3u1t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:54, 13 July 2022) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3u1t.jpg|left|200px]]
 
-
<!--
+
==Haloalkane Dehalogenase, DmmA, of marine microbial origin==
-
The line below this paragraph, containing "STRUCTURE_3u1t", creates the "Structure Box" on the page.
+
<StructureSection load='3u1t' size='340' side='right'caption='[[3u1t]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3u1t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Miscellaneous_nucleic_acid Miscellaneous nucleic acid]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U1T FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-
-->
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_3u1t| PDB=3u1t | SCENE= }}
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1t OCA], [https://pdbe.org/3u1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u1t RCSB], [https://www.ebi.ac.uk/pdbsum/3u1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1t ProSAT]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
DmmA is a haloalkane dehalogenase (HLD) identified and characterized from the metagenomic DNA of a marine microbial consortium. Dehalogenase activity was detected with 1,3-dibromopropane as substrate, with steady-state kinetic parameters typical of HLDs (K(m) =0.24+/-0.05 mM, k(cat) =2.4+/-0.1 s-1). The 2.2-A crystal structure of DmmA revealed a fold and active site similar to other HLDs, but with a substantially larger active site binding pocket, suggestive of an ability to act on bulky substrates. This enhanced cavity was shown to accept a range of linear and cyclic substrates, suggesting that DmmA will contribute to the expanding industrial applications of HLDs.
-
===Haloalkane Dehalogenase, DmmA, of marine microbial origin===
+
Structure and activity of DmmA, a marine haloalkane dehalogenase.,Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL Protein Sci. 2011 Nov 28. doi: 10.1002/pro.2009. PMID:22124946<ref>PMID:22124946</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3u1t" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_22124946}}, adds the Publication Abstract to the page
+
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 22124946 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_22124946}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
[[3u1t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1T OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:022124946</ref><references group="xtra"/>
+
[[Category: Haloalkane dehalogenase]]
[[Category: Haloalkane dehalogenase]]
-
[[Category: Unidentified]]
+
[[Category: Large Structures]]
 +
[[Category: Miscellaneous nucleic acid]]
[[Category: Gehret, J J]]
[[Category: Gehret, J J]]
-
[[Category: Smith, J L.]]
+
[[Category: Smith, J L]]
[[Category: Alpha/beta-hydrolase]]
[[Category: Alpha/beta-hydrolase]]
-
[[Category: Haloalkane dehalogenase]]
 
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Current revision

Haloalkane Dehalogenase, DmmA, of marine microbial origin

PDB ID 3u1t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3u1t"
Personal tools