3uvj

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[[Image:3uvj.jpg|left|200px]]
 
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==Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.==
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The line below this paragraph, containing "STRUCTURE_3uvj", creates the "Structure Box" on the page.
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<StructureSection load='3uvj' size='340' side='right'caption='[[3uvj]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3uvj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UVJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_3uvj| PDB=3uvj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvj OCA], [https://pdbe.org/3uvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uvj RCSB], [https://www.ebi.ac.uk/pdbsum/3uvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvj ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/GCYA1_HUMAN GCYA1_HUMAN] Moyamoya disease with early-onset achalasia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/GCYA1_HUMAN GCYA1_HUMAN]
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===Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.===
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==See Also==
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*[[Guanylate cyclase 3D structures|Guanylate cyclase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3uvj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVJ OCA].
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[[Category: Guanylate cyclase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allerston, C K.]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Allerston CK]]
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[[Category: Berridge, G.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Berridge G]]
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[[Category: Chalk, R.]]
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[[Category: Bountra C]]
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[[Category: Cooper, C D.O.]]
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[[Category: Chalk R]]
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[[Category: Delft, F Von.]]
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[[Category: Cooper CDO]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Gileadi, O.]]
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[[Category: Gileadi O]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Savitsky P]]
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[[Category: Savitsky, P.]]
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[[Category: Vollmar M]]
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[[Category: Vollmar, M.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Von Delft F]]
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[[Category: Cgmp biosynthesis]]
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[[Category: Cystol]]
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[[Category: Gtp binding metal-binding]]
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[[Category: Lyase]]
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[[Category: Nitric oxide]]
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[[Category: Nucleotide-binding]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.

PDB ID 3uvj

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OCA

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