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3u1y

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[[Image:3u1y.jpg|left|200px]]
 
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==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==
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The line below this paragraph, containing "STRUCTURE_3u1y", creates the "Structure Box" on the page.
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<StructureSection load='3u1y' size='340' side='right'caption='[[3u1y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3u1y| PDB=3u1y | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [https://pdbe.org/3u1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [https://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
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===Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections===
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==See Also==
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures|UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22175825 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22175825}}
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==About this Structure==
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[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA].
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==Reference==
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<ref group="xtra">PMID:022175825</ref><references group="xtra"/>
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Abramite, J.]]
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[[Category: Brown, M.]]
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[[Category: Liu, S.]]
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[[Category: Gram negative]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Lpxc]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Abramite J]]
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[[Category: Brown M]]
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[[Category: Liu S]]

Current revision

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

PDB ID 3u1y

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