3stj

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[[Image:3stj.png|left|200px]]
 
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==Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli==
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The line below this paragraph, containing "STRUCTURE_3stj", creates the "Structure Box" on the page.
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<StructureSection load='3stj' size='340' side='right'caption='[[3stj]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3stj]] is a 25 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3STJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3STJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3stj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3stj OCA], [https://pdbe.org/3stj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3stj RCSB], [https://www.ebi.ac.uk/pdbsum/3stj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3stj ProSAT]</span></td></tr>
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{{STRUCTURE_3stj| PDB=3stj | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli===
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[https://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref>
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== References ==
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<references/>
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21685389 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21685389}}
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==About this Structure==
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[[3stj]] is a 25 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3STJ OCA].
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==Reference==
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<ref group="xtra">PMID:021685389</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Canellas, F.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Clausen, T.]]
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[[Category: Large Structures]]
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[[Category: Ehrmann, M.]]
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[[Category: Canellas F]]
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[[Category: Krojer, T.]]
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[[Category: Clausen T]]
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[[Category: Malet, H.]]
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[[Category: Ehrmann M]]
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[[Category: Sawa, J.]]
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[[Category: Krojer T]]
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[[Category: Chaperone]]
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[[Category: Malet H]]
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[[Category: Degp]]
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[[Category: Sawa J]]
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[[Category: Degq]]
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[[Category: Hydrolase]]
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[[Category: Pdz domain]]
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[[Category: Protease]]
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[[Category: Serine protease]]
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Current revision

Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli

PDB ID 3stj

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