2lf3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:42, 15 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2lf3.png|left|200px]]
 
-
<!--
+
==Solution NMR structure of HopPmaL_281_385 from Pseudomonas syringae pv. maculicola str. ES4326, Midwest Center for Structural Genomics target APC40104.5 and Northeast Structural Genomics Consortium target PsT2A==
-
The line below this paragraph, containing "STRUCTURE_2lf3", creates the "Structure Box" on the page.
+
<StructureSection load='2lf3' size='340' side='right'caption='[[2lf3]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2lf3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._maculicola Pseudomonas syringae pv. maculicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LF3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lf3 OCA], [https://pdbe.org/2lf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2lf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lf3 ProSAT]</span></td></tr>
-
{{STRUCTURE_2lf3| PDB=2lf3 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HPAB3_PSEYM HPAB3_PSEYM] Effector protein involved in gene-for-gene resistance in tomato plants. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible plants, promotes virulence, in part, by enhancing the development of disease symptoms and bacterial growth.
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
HopPmaL is a member of the HopAB family of type III effectors present in the phytopathogen Pseudomonas syringae. Using both X-ray crystallography and solution nuclear magnetic resonance, we demonstrate that HopPmaL contains two structurally homologous yet functionally distinct domains. The N-terminal domain corresponds to the previously described Pto-binding domain, while the previously uncharacterised C-terminal domain spans residues 308-385. While structurally similar, these domains do not share significant sequence similarity and most importantly demonstrate significant differences in key residues involved in host protein recognition, suggesting that each of them targets a different host protein.
-
===Solution NMR structure of HopPmaL_281_385 from Pseudomonas syringae pv. maculicola str. ES4326, Midwest Center for Structural Genomics target APC40104.5 and Northeast Structural Genomics Consortium target PsT2A===
+
Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.,Singer AU, Wu B, Yee A, Houliston S, Xu X, Cui H, Skarina T, Garcia M, Semesi A, Arrowsmith CH, Savchenko A Biochemistry. 2012 Jan 10;51(1):1-3. Epub 2011 Dec 28. PMID:22191472<ref>PMID:22191472</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 2lf3" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_22191472}}, adds the Publication Abstract to the page
+
*[[Avirulence protein 3D structures|Avirulence protein 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 22191472 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_22191472}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
[[2lf3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._maculicola Pseudomonas syringae pv. maculicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF3 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:022191472</ref><references group="xtra"/>
+
[[Category: Pseudomonas syringae pv. maculicola]]
[[Category: Pseudomonas syringae pv. maculicola]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Garcia, M.]]
+
[[Category: Garcia M]]
-
[[Category: Houliston, S.]]
+
[[Category: Houliston S]]
-
[[Category: Joachimiak, A.]]
+
[[Category: Joachimiak A]]
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
[[Category: Montelione GT]]
-
[[Category: Montelione, G T.]]
+
[[Category: Savchenko A]]
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
[[Category: Semesi A]]
-
[[Category: OCSP, Ontario Centre for Structural Proteomics.]]
+
[[Category: Singer AU]]
-
[[Category: Savchenko, A.]]
+
[[Category: Wu B]]
-
[[Category: Semesi, A.]]
+
[[Category: Yee A]]
-
[[Category: Singer, A U.]]
+
-
[[Category: Wu, B.]]
+
-
[[Category: Yee, A.]]
+
-
[[Category: Mcsg]]
+
-
[[Category: Midwest center for structural genomic]]
+
-
[[Category: Nesg]]
+
-
[[Category: Northeast structural genomics consortium]]
+
-
[[Category: Ocsp]]
+
-
[[Category: Ontario centre for structural proteomic]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Type iii effector]]
+

Current revision

Solution NMR structure of HopPmaL_281_385 from Pseudomonas syringae pv. maculicola str. ES4326, Midwest Center for Structural Genomics target APC40104.5 and Northeast Structural Genomics Consortium target PsT2A

PDB ID 2lf3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2lf3"
Personal tools