3uwd

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[[Image:3uwd.png|left|200px]]
 
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==Crystal Structure of Phosphoglycerate Kinase from Bacillus Anthracis==
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The line below this paragraph, containing "STRUCTURE_3uwd", creates the "Structure Box" on the page.
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<StructureSection load='3uwd' size='340' side='right'caption='[[3uwd]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3uwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3b2b 3b2b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UWD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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{{STRUCTURE_3uwd| PDB=3uwd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uwd OCA], [https://pdbe.org/3uwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uwd RCSB], [https://www.ebi.ac.uk/pdbsum/3uwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uwd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGK_BACAN PGK_BACAN]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Phosphoglycerate kinase (PGK) is indispensable during glycolysis for anaerobic glucose degradation and energy generation. Here we present comprehensive structure analysis of two putative PGKs from Bacillus anthracis str. Sterne and Campylobacter jejuni in the context of their structural homologs. They are the first PGKs from pathogenic bacteria reported in the Protein Data Bank. The crystal structure of PGK from Bacillus anthracis str. Sterne (BaPGK) has been determined at 1.68 A while the structure of PGK from Campylobacter jejuni (CjPGK) has been determined at 2.14 A resolution. The proteins' monomers are composed of two domains, each containing a Rossmann fold, hinged together by a helix which can be used to adjust the relative position between two domains. It is also shown that apo-forms of both BaPGK and CjPGK adopt open conformations as compared to the substrate and ATP bound forms of PGK from other species.
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===Crystal Structure of Phosphoglycerate Kinase from Bacillus Anthracis===
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Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.,Zheng H, Filippova EV, Tkaczuk KL, Dworzynski P, Chruszcz M, Porebski PJ, Wawrzak Z, Onopriyenko O, Kudritska M, Grimshaw S, Savchenko A, Anderson WF, Minor W J Struct Funct Genomics. 2012 Mar;13(1):15-26. Epub 2012 Mar 10. PMID:22403005<ref>PMID:22403005</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3uwd" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[3uwd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3b2b 3b2b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UWD OCA].
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*[[Phosphoglycerate kinase 3D structures|Phosphoglycerate kinase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Phosphoglycerate kinase]]
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[[Category: Large Structures]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson WF]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Chruszcz M]]
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[[Category: Chruszcz, M.]]
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[[Category: Grimshaw S]]
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[[Category: Grimshaw, S.]]
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[[Category: Kudritska M]]
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[[Category: Kudritska, M.]]
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[[Category: Minor W]]
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[[Category: Minor, W.]]
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[[Category: Porebski P]]
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[[Category: Porebski, P.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: Zheng H]]
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[[Category: Zheng, H.]]
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[[Category: Anthrax]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Phosphoglycerate]]
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[[Category: Phosphoglycerate kinase]]
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[[Category: Phosphorylation]]
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[[Category: Rossmann fold]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Phosphoglycerate Kinase from Bacillus Anthracis

PDB ID 3uwd

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