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3u01
From Proteopedia
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| - | [[Image:3u01.png|left|200px]] | ||
| - | + | ==Crystal structure of onconase double mutant C30A/C75A at 1.12 A resolution== | |
| - | + | <StructureSection load='3u01' size='340' side='right'caption='[[3u01]], [[Resolution|resolution]] 1.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3u01]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U01 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u01 OCA], [https://pdbe.org/3u01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u01 RCSB], [https://www.ebi.ac.uk/pdbsum/3u01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u01 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | [[3u01]] is a 1 chain structure with sequence from [ | + | [[Category: Large Structures]] |
| - | [[ | + | [[Category: Lithobates pipiens]] |
| - | [[ | + | [[Category: Kurpiewska K]] |
| - | [[ | + | [[Category: Lewinski K]] |
| - | [ | + | [[Category: Loch J]] |
| - | [ | + | [[Category: Ribo M]] |
| - | [[Category: | + | [[Category: Torrent G]] |
| - | [[Category: | + | [[Category: Vilanova M]] |
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Current revision
Crystal structure of onconase double mutant C30A/C75A at 1.12 A resolution
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