2klc
From Proteopedia
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- | [[Image:2klc.png|left|200px]] | ||
- | + | ==NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A== | |
- | + | <StructureSection load='2klc' size='340' side='right'caption='[[2klc]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLC FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [https://pdbe.org/2klc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [https://www.ebi.ac.uk/pdbsum/2klc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation. | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | < | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/2klc_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2klc ConSurf]. |
- | [[2klc]] is a 1 chain structure with sequence from [ | + | <div style="clear:both"></div> |
- | + | __TOC__ | |
- | == | + | </StructureSection> |
- | < | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
- | [[Category: Dhe-Paganon | + | [[Category: Arrowsmith CH]] |
- | [[Category: Doherty | + | [[Category: Dhe-Paganon S]] |
- | [[Category: Fares | + | [[Category: Doherty RS]] |
- | [[Category: Garcia | + | [[Category: Fares C]] |
- | [[Category: Gutmanas | + | [[Category: Garcia M]] |
- | [[Category: Lemak | + | [[Category: Gutmanas A]] |
- | [[Category: Montelione | + | [[Category: Lemak S]] |
- | + | [[Category: Montelione GT]] | |
- | + | [[Category: Yee A]] | |
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- | [[Category: Yee | + | |
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Current revision
NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Dhe-Paganon S | Doherty RS | Fares C | Garcia M | Gutmanas A | Lemak S | Montelione GT | Yee A