2klc

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m (Protected "2klc" [edit=sysop:move=sysop])
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[[Image:2klc.png|left|200px]]
 
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==NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A==
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The line below this paragraph, containing "STRUCTURE_2klc", creates the "Structure Box" on the page.
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<StructureSection load='2klc' size='340' side='right'caption='[[2klc]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [https://pdbe.org/2klc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [https://www.ebi.ac.uk/pdbsum/2klc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</span></td></tr>
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{{STRUCTURE_2klc| PDB=2klc | SCENE= }}
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</table>
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== Function ==
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===NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A===
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[https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_21161328}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 21161328 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/2klc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_21161328}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2klc ConSurf].
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[[2klc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021161328</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Dhe-Paganon, S.]]
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[[Category: Arrowsmith CH]]
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[[Category: Doherty, R S.]]
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[[Category: Dhe-Paganon S]]
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[[Category: Fares, C.]]
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[[Category: Doherty RS]]
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[[Category: Garcia, M.]]
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[[Category: Fares C]]
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[[Category: Gutmanas, A.]]
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[[Category: Garcia M]]
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[[Category: Lemak, S.]]
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[[Category: Gutmanas A]]
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[[Category: Montelione, G T.]]
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[[Category: Lemak S]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: OCSP, Ontario Centre for Structural Proteomics.]]
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[[Category: Yee A]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Yee, A.]]
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[[Category: Alzheimers']]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Nucleus]]
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[[Category: Ocsp]]
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[[Category: Ontario centre for structural proteomic]]
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[[Category: Phosphoprotein]]
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[[Category: Proteasome]]
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[[Category: Protein binding]]
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[[Category: Protein degradation]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Ubiquitin ligase-associated]]
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[[Category: Ubiquitin-like]]
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[[Category: Ubiquitination]]
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[[Category: Ubl]]
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[[Category: Unknown function]]
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Current revision

NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A

PDB ID 2klc

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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