3tw3

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[[Image:3tw3.png|left|200px]]
 
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==Crystal structure of RtcA.ATP.Co ternary complex==
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The line below this paragraph, containing "STRUCTURE_3tw3", creates the "Structure Box" on the page.
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<StructureSection load='3tw3' size='340' side='right'caption='[[3tw3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3tw3| PDB=3tw3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw3 OCA], [https://pdbe.org/3tw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw3 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of RtcA.ATP.Co ternary complex===
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== Function ==
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[https://www.uniprot.org/uniprot/RTCA_ECOLI RTCA_ECOLI] Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.<ref>PMID:9738023</ref>
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22167800 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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{{ABSTRACT_PUBMED_22167800}}
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[[Category: Large Structures]]
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[[Category: Chakravarty AK]]
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==About this Structure==
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[[Category: Shuman S]]
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[[3tw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW3 OCA].
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[[Category: Smith P]]
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==Reference==
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<ref group="xtra">PMID:022167800</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
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[[Category: RNA-3'-phosphate cyclase]]
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[[Category: Chakravarty, A K.]]
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[[Category: Shuman, S.]]
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[[Category: Smith, P.]]
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[[Category: Cyclase family]]
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[[Category: Cyclizing rna 3'-phosphate end]]
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[[Category: Transferase]]
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Current revision

Crystal structure of RtcA.ATP.Co ternary complex

PDB ID 3tw3

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