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4del
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4del is ON HOLD Authors: Pegan, S.D., Mesecar, A.D. Description: Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis== | |
| + | <StructureSection load='4del' size='340' side='right'caption='[[4del]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4del]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DEL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC+ACID'>PGH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4del FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4del OCA], [https://pdbe.org/4del PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4del RCSB], [https://www.ebi.ac.uk/pdbsum/4del PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4del ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALF_MYCTU ALF_MYCTU] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Aldolase 3D structures|Aldolase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Mesecar AD]] | ||
| + | [[Category: Pegan SD]] | ||
Current revision
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis
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