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3upp
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of penicillin-binding protein A from M. tuberculosis: ceftrixaone acyl-enzyme complex== | |
| + | <StructureSection load='3upp' size='340' side='right'caption='[[3upp]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3upp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UPP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3upp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3upp OCA], [https://pdbe.org/3upp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3upp RCSB], [https://www.ebi.ac.uk/pdbsum/3upp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3upp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PBPA_MYCTU PBPA_MYCTU] Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation. | ||
| - | + | ==See Also== | |
| - | + | *[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Davies C]] | ||
| + | [[Category: Fedorovich A]] | ||
Current revision
Structure of penicillin-binding protein A from M. tuberculosis: ceftrixaone acyl-enzyme complex
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