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3r44

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[[Image:3r44.jpg|left|200px]]
 
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==Mycobacterium tuberculosis fatty acyl CoA synthetase==
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The line below this paragraph, containing "STRUCTURE_3r44", creates the "Structure Box" on the page.
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<StructureSection load='3r44' size='340' side='right'caption='[[3r44]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3r44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R44 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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{{STRUCTURE_3r44| PDB=3r44 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r44 OCA], [https://pdbe.org/3r44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r44 RCSB], [https://www.ebi.ac.uk/pdbsum/3r44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r44 ProSAT]</span></td></tr>
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</table>
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===Mycobacterium tuberculosis fatty acyl CoA synthetase===
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== Function ==
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[https://www.uniprot.org/uniprot/FAC13_MYCTU FAC13_MYCTU] Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH. Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. It has preference for the fatty acid with long chain length in the following order: hexacosanoic acid (C26), tetracosanoic acid (C24) and palmitic acid (C16).<ref>PMID:15937179</ref> <ref>PMID:20027301</ref> <ref>PMID:22560731</ref>
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== References ==
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==About this Structure==
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<references/>
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[[3r44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R44 OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Andersson, C S.]]
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[[Category: Andersson CS]]
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[[Category: Hogbom, M.]]
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[[Category: Hogbom M]]
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[[Category: Molina, D Martinez.]]
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[[Category: Martinez Molina D]]
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[[Category: Acyl coa synthetase]]
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[[Category: Ligase]]
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Current revision

Mycobacterium tuberculosis fatty acyl CoA synthetase

PDB ID 3r44

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OCA

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