3zse

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[[Image:3zse.jpg|left|200px]]
 
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==3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca==
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The line below this paragraph, containing "STRUCTURE_3zse", creates the "Structure Box" on the page.
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<StructureSection load='3zse' size='340' side='right'caption='[[3zse]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3zse]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZSE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=X2F:2-DEOXY-2-FLUORO+XYLOPYRANOSE'>X2F</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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{{STRUCTURE_3zse| PDB=3zse | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zse OCA], [https://pdbe.org/3zse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zse RCSB], [https://www.ebi.ac.uk/pdbsum/3zse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zse ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5RZ98_THEFU Q5RZ98_THEFU]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Thermostable enzymes employ various structural features dictated at the amino-acid sequence level that allow them to maintain their integrity at higher temperatures. Many hypotheses as to the nature of thermal stability have been proposed, including optimized core hydrophobicity and an increase in charged surface residues to enhance polar solvent interactions for solubility. Here, the three-dimensional structure of the family GH11 xylanase from the moderate thermophile Thermobifida fusca in its trapped covalent glycosyl-enzyme intermediate complex is presented. Interactions with the bound ligand show fewer direct hydrogen bonds from ligand to protein than observed in previous complexes from other species and imply that binding of the xylan substrate involves several water-mediated hydrogen bonds.
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===3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca===
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Three-dimensional structure of a thermophilic family GH11 xylanase from Thermobifida fusca.,van Bueren AL, Otani S, Friis EP, Wilson KS, Davies GJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):141-4. Epub, 2012 Jan 25. PMID:22297985<ref>PMID:22297985</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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[[3zse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSE OCA].
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<div class="pdbe-citations 3zse" style="background-color:#fffaf0;"></div>
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[[Category: Endo-1,4-beta-xylanase]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermobifida fusca]]
[[Category: Thermobifida fusca]]
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[[Category: Bueren, A Lammerts Van.]]
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[[Category: Davies GJ]]
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[[Category: Davies, G J.]]
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[[Category: Friis EP]]
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[[Category: Friis, E P.]]
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[[Category: Lammerts van Bueren A]]
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[[Category: Otani, S.]]
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[[Category: Otani S]]
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[[Category: Wilson, K S.]]
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[[Category: S Wilson K]]
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[[Category: Glycoside hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Plant cell wall]]
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Current revision

3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca

PDB ID 3zse

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