This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4dne
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4dne is ON HOLD Authors: Panwar, P., Deniaud, A., Pebay-Peyroula, E. Description: Crystal structure of a triple-mutant of streptavidin in complex w...) |
|||
| (10 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a triple-mutant of streptavidin in complex with desthiobiotin== | |
| + | <StructureSection load='4dne' size='340' side='right'caption='[[4dne]], [[Resolution|resolution]] 1.88Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4dne]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DNE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTB:6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC+ACID'>DTB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dne OCA], [https://pdbe.org/4dne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dne RCSB], [https://www.ebi.ac.uk/pdbsum/4dne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dne ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin). | ||
| - | + | ==See Also== | |
| - | + | *[[Avidin 3D structures|Avidin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptomyces avidinii]] | ||
| + | [[Category: Deniaud A]] | ||
| + | [[Category: Panwar P]] | ||
| + | [[Category: Pebay-Peyroula E]] | ||
Current revision
Crystal structure of a triple-mutant of streptavidin in complex with desthiobiotin
| |||||||||||
