3tpz

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[[Image:3tpz.jpg|left|200px]]
 
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==2.1 Angstrom crystal structure of the L114P mutant of E. Coli KsgA==
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The line below this paragraph, containing "STRUCTURE_3tpz", creates the "Structure Box" on the page.
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<StructureSection load='3tpz' size='340' side='right'caption='[[3tpz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tpz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TPZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3tpz| PDB=3tpz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpz OCA], [https://pdbe.org/3tpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tpz RCSB], [https://www.ebi.ac.uk/pdbsum/3tpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RSMA_ECOLI RSMA_ECOLI] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Has also a DNA glycosylase/AP lyase activity that removes C mispaired with oxidized T from DNA, and may play a role in protection of DNA against oxidative stress.<ref>PMID:3905517</ref> <ref>PMID:19223326</ref> <ref>PMID:18990185</ref>
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===2.1 Angstrom crystal structure of the L114P mutant of E. Coli KsgA===
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==See Also==
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*[[Adenosine dimethyltransferase 3D structures|Adenosine dimethyltransferase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22142337 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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{{ABSTRACT_PUBMED_22142337}}
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[[Category: Large Structures]]
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[[Category: Musayev FN]]
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==About this Structure==
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[[Category: Rife JP]]
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[[3tpz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPZ OCA].
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[[Category: Scarsdale JN]]
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==Reference==
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<ref group="xtra">PMID:022142337</ref><ref group="xtra">PMID:020163168</ref><ref group="xtra">PMID:019520088</ref><ref group="xtra">PMID:015136037</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
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[[Category: Musayev, F N.]]
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[[Category: Rife, J P.]]
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[[Category: Scarsdale, J N.]]
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[[Category: Ribogenesis]]
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[[Category: Rrna adenine dimethyltransferase]]
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[[Category: Transferase]]
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Current revision

2.1 Angstrom crystal structure of the L114P mutant of E. Coli KsgA

PDB ID 3tpz

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