3t5k

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[[Image:3t5k.jpg|left|200px]]
 
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==Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 14-mer) with Dpo4 and incoming dDTP==
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The line below this paragraph, containing "STRUCTURE_3t5k", creates the "Structure Box" on the page.
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<StructureSection load='3t5k' size='340' side='right'caption='[[3t5k]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3t5k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T5K FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=HN0:2-DEOXY-N-[(2S,3S,5R)-5-HYDROXY-2-PENTYLTETRAHYDROFURAN-3-YL]GUANOSINE+5-(DIHYDROGEN+PHOSPHATE)'>HN0</scene></td></tr>
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{{STRUCTURE_3t5k| PDB=3t5k | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t5k OCA], [https://pdbe.org/3t5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t5k RCSB], [https://www.ebi.ac.uk/pdbsum/3t5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t5k ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
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===Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 14-mer) with Dpo4 and incoming dDTP===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_22313351}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22313351 is the PubMed ID number.
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[[Category: Saccharolobus solfataricus P2]]
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[[Category: Banerjee S]]
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{{ABSTRACT_PUBMED_22313351}}
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[[Category: Christov PP]]
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[[Category: Kozekova A]]
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==About this Structure==
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[[Category: Rizzo CJ]]
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[[3t5k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5K OCA].
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[[Category: Stone MP]]
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==Reference==
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<ref group="xtra">PMID:022313351</ref><references group="xtra"/>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Sulfolobus solfataricus p2]]
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[[Category: Banerjee, S.]]
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[[Category: Christov, P P.]]
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[[Category: Kozekova, A.]]
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[[Category: Rizzo, C J.]]
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[[Category: Stone, M P.]]
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[[Category: Dna polymerase]]
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[[Category: Dna-transferase complex]]
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[[Category: Hne]]
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[[Category: Ternary complex of dpo4-dna-datp]]
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Current revision

Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 14-mer) with Dpo4 and incoming dDTP

PDB ID 3t5k

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