3j05
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab== | |
| - | + | <SX load='3j05' size='340' side='right' viewer='molstar' caption='[[3j05]], [[Resolution|resolution]] 7.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3j05]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J05 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j05 OCA], [https://pdbe.org/3j05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j05 RCSB], [https://www.ebi.ac.uk/pdbsum/3j05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j05 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q689G3_9FLAV Q689G3_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774] | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Dengue virus 1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Alonso S]] | ||
| + | [[Category: Chan SH]] | ||
| + | [[Category: Fisher D]] | ||
| + | [[Category: Hanson B]] | ||
| + | [[Category: Kemeny DM]] | ||
| + | [[Category: Kukkaro P]] | ||
| + | [[Category: Leo YS]] | ||
| + | [[Category: Lim A]] | ||
| + | [[Category: Lok SM]] | ||
| + | [[Category: MacAry PA]] | ||
| + | [[Category: Ng G]] | ||
| + | [[Category: Ng ML]] | ||
| + | [[Category: Ooi EE]] | ||
| + | [[Category: Schul W]] | ||
| + | [[Category: Shi PY]] | ||
| + | [[Category: Smith KGC]] | ||
| + | [[Category: Tan TT]] | ||
| + | [[Category: Teo EW]] | ||
| + | [[Category: Teoh EP]] | ||
| + | [[Category: Yip A]] | ||
Current revision
Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab
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