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4dpm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of malonyl-coenzyme A reductase from crenarchaeota in complex with CoA== | |
| - | + | <StructureSection load='4dpm' size='340' side='right'caption='[[4dpm]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4dpm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DPM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dpm OCA], [https://pdbe.org/4dpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dpm RCSB], [https://www.ebi.ac.uk/pdbsum/4dpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dpm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MCR_SULTO MCR_SULTO] Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles. Can also use succinyl-CoA and succinate semialdehyde as substrates but at a lower rate than malonyl-CoA.<ref>PMID:17041055</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sulfurisphaera tokodaii str. 7]] | ||
| + | [[Category: Demmer U]] | ||
| + | [[Category: Ermler U]] | ||
| + | [[Category: Fuchs G]] | ||
| + | [[Category: Kockelkorn D]] | ||
| + | [[Category: Srivastava A]] | ||
| + | [[Category: Warkentin E]] | ||
Current revision
Structure of malonyl-coenzyme A reductase from crenarchaeota in complex with CoA
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