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4dq1

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(New page: '''Unreleased structure''' The entry 4dq1 is ON HOLD Authors: OSIPIUK, J., Holowicki, J., Jedrzejczak, R., Rubin, E., Guinn, K., Ioerger, T., Baker, D., Sacchettini, J., JOACHIMIAK, A.,...)
Current revision (14:42, 14 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4dq1 is ON HOLD
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==Thymidylate synthase from Staphylococcus aureus.==
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<StructureSection load='4dq1' size='340' side='right'caption='[[4dq1]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dq1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DQ1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dq1 OCA], [https://pdbe.org/4dq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dq1 RCSB], [https://www.ebi.ac.uk/pdbsum/4dq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dq1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TYSY_STAAM TYSY_STAAM] Provides the sole de novo source of dTMP for DNA biosynthesis.[HAMAP-Rule:MF_00008]
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Authors: OSIPIUK, J., Holowicki, J., Jedrzejczak, R., Rubin, E., Guinn, K., Ioerger, T., Baker, D., Sacchettini, J., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI)
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==See Also==
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*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
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Description: Thymidylate synthase from Staphylococcus aureus.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Baker D]]
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[[Category: Guinn K]]
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[[Category: Holowicki J]]
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[[Category: Ioerger T]]
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[[Category: Jedrzejczak R]]
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[[Category: Joachimiak A]]
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[[Category: Osipiuk J]]
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[[Category: Rubin E]]
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[[Category: Sacchettini J]]

Current revision

Thymidylate synthase from Staphylococcus aureus.

PDB ID 4dq1

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