3qbt

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[[Image:3qbt.png|left|200px]]
 
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==Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp==
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The line below this paragraph, containing "STRUCTURE_3qbt", creates the "Structure Box" on the page.
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<StructureSection load='3qbt' size='340' side='right'caption='[[3qbt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qbt]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3qbt| PDB=3qbt | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbt OCA], [https://pdbe.org/3qbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbt RCSB], [https://www.ebi.ac.uk/pdbsum/3qbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAB8A_HUMAN RAB8A_HUMAN] May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.<ref>PMID:20890297</ref> <ref>PMID:21282656</ref>
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===Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp===
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==See Also==
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*[[Inositol polyphosphate 5-phosphatase OCRL|Inositol polyphosphate 5-phosphatase OCRL]]
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
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*[[3D structures of inositol polyphosphate 5-phosphatase OCRL|3D structures of inositol polyphosphate 5-phosphatase OCRL]]
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== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 21378754 is the PubMed ID number.
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<references/>
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__TOC__
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{{ABSTRACT_PUBMED_21378754}}
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</StructureSection>
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==About this Structure==
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[[3qbt]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBT OCA].
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==Reference==
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<ref group="xtra">PMID:021378754</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Phosphoinositide 5-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Blankenfeldt, W.]]
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[[Category: Blankenfeldt W]]
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[[Category: Erdmann, K S.]]
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[[Category: Erdmann KS]]
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[[Category: Goody, R S.]]
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[[Category: Goody RS]]
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[[Category: Hagemann, N.]]
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[[Category: Hagemann N]]
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[[Category: Hou, X.]]
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[[Category: Hou X]]
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[[Category: Itzen, A.]]
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[[Category: Itzen A]]
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[[Category: Schoebel, S.]]
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[[Category: Schoebel S]]
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[[Category: Appl1]]
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[[Category: Ash]]
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[[Category: Clathrin]]
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[[Category: Endocytosis]]
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[[Category: Gtpase]]
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[[Category: Immunoglobulin fold]]
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[[Category: Lowe syndrome]]
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[[Category: Ocrl1]]
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[[Category: Phosphoinositide]]
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[[Category: Protein transport]]
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[[Category: Protein transport-hydrolase complex]]
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[[Category: Rab8a]]
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[[Category: Rhogap]]
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[[Category: Vesicular trafficking]]
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Current revision

Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp

PDB ID 3qbt

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