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3skm

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[[Image:3skm.jpg|left|200px]]
 
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==Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide==
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The line below this paragraph, containing "STRUCTURE_3skm", creates the "Structure Box" on the page.
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<StructureSection load='3skm' size='340' side='right'caption='[[3skm]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3skm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SKM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3skm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3skm OCA], [https://pdbe.org/3skm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3skm RCSB], [https://www.ebi.ac.uk/pdbsum/3skm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3skm ProSAT]</span></td></tr>
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{{STRUCTURE_3skm| PDB=3skm | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EBNA3_EBVG EBNA3_EBVG] Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop (By similarity).
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===Crystal Structure of a peptide-HLA structure===
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==See Also==
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22140258 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22140258}}
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==About this Structure==
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[[3skm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SKM OCA].
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==Reference==
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<ref group="xtra">PMID:022140258</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Burrows, S R.]]
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[[Category: Human gammaherpesvirus 4]]
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[[Category: Chih, L Yu.]]
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[[Category: Large Structures]]
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[[Category: Gras, S.]]
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[[Category: Burrows SR]]
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[[Category: Hanim, H.]]
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[[Category: Gras S]]
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[[Category: Kjer-Nielsen, L.]]
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[[Category: Hanim H]]
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[[Category: Mccluskey, J.]]
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[[Category: Kjer-Nielsen L]]
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[[Category: Purcell, A W.]]
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[[Category: Mccluskey J]]
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[[Category: Rossjohn, J.]]
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[[Category: Purcell AW]]
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[[Category: Wilmann, P G.]]
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[[Category: Rossjohn J]]
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[[Category: Zhenjun, C.]]
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[[Category: Wilmann PG]]
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[[Category: Immune system]]
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[[Category: Yu Chih L]]
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[[Category: T cell receptor]]
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[[Category: Zhenjun C]]

Current revision

Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide

PDB ID 3skm

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