3rjo

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[[Image:3rjo.png|left|200px]]
 
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==Crystal Structure of ERAP1 Peptide Binding Domain==
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The line below this paragraph, containing "STRUCTURE_3rjo", creates the "Structure Box" on the page.
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<StructureSection load='3rjo' size='340' side='right'caption='[[3rjo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3rjo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_3rjo| PDB=3rjo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjo OCA], [https://pdbe.org/3rjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjo RCSB], [https://www.ebi.ac.uk/pdbsum/3rjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjo ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes. To examine ERAP1's unique properties of length- and sequence-dependent processing of antigen precursors, we report a 2.3 A resolution complex structure of the ERAP1 regulatory domain. Our study reveals a binding conformation of ERAP1 to the carboxyl terminus of a peptide, and thus provides direct evidence for the molecular ruler mechanism.
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===Crystal Structure of ERAP1 Peptide Binding Domain===
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Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1.,Gandhi A, Lakshminarasimhan D, Sun Y, Guo HC Sci Rep. 2011;1:186. Epub 2011 Dec 13. PMID:22355701<ref>PMID:22355701</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3rjo" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_22355701}}, adds the Publication Abstract to the page
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22355701 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22355701}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[3rjo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJO OCA].
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==Reference==
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<ref group="xtra">PMID:022355701</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Gandhi, A.]]
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[[Category: Large Structures]]
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[[Category: Guo, H C.]]
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[[Category: Gandhi A]]
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[[Category: Lakshminarasimhan, D.]]
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[[Category: Guo H-C]]
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[[Category: Aminopeptidase]]
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[[Category: Lakshminarasimhan D]]
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[[Category: Erap1]]
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[[Category: Hydrolase]]
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Current revision

Crystal Structure of ERAP1 Peptide Binding Domain

PDB ID 3rjo

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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