4dyu
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4dyu is ON HOLD Authors: Tan, K., Gu, M., Kwon, K., Anderson, W.F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Center for Struct...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10== |
| + | <StructureSection load='4dyu' size='340' side='right'caption='[[4dyu]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4dyu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_KIM10+ Yersinia pestis KIM10+]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DYU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dyu OCA], [https://pdbe.org/4dyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dyu RCSB], [https://www.ebi.ac.uk/pdbsum/4dyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dyu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPS_YERPE DPS_YERPE] During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.[HAMAP-Rule:MF_01441] | ||
| - | + | ==See Also== | |
| - | + | *[[Ferritin 3D structures|Ferritin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Yersinia pestis KIM10+]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Gu M]] | ||
| + | [[Category: Joachimiak A]] | ||
| + | [[Category: Kwon K]] | ||
| + | [[Category: Tan K]] | ||
Current revision
The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10
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