4dxl

==Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abscessus, bound to CMP and ATP==

== Structural highlights ==

<table><tr><td colspan='2'>[[4dxl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacteroides_abscessus_ATCC_19977 Mycobacteroides abscessus ATCC 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DXL FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxl OCA], [https://pdbe.org/4dxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dxl RCSB], [https://www.ebi.ac.uk/pdbsum/4dxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxl ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/B1MKD5_MYCA9 B1MKD5_MYCA9] Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity).[HAMAP-Rule:MF_00061]

[[Category: Large Structures]]

[[Category: Mycobacteroides abscessus ATCC 19977]]