Signal recognition particle receptor

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<Structure load='2fh5' size='400' frame='true' align='right' caption='Human SRPR complex with GTP [[2fh5]]' scene= />
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<StructureSection load='' size='350' side='right' scene='48/485587/Cv/1' caption='Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion [[2fh5]]'>
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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase.
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==3D structures of SRPR==
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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called '''FtsY'''.
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[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
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See also [[Intracellular receptors]]
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[[2fh5]] - hSRPR α+β subunits + GTP – human<br />
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[[2ged]] - ySRPR β subunit (mutant)<br />
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[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
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[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
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*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.
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*<scene name='48/485587/Cv/7'>Mg coordination site</scene>.
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==3D structures of signal recognition particle receptor==
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[[Signal recognition particle receptor 3D structures]]
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</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion 2fh5

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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