4dhi
From Proteopedia
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- | [[Image:4dhi.png|left|200px]] | ||
- | < | + | ==Structure of C. elegans OTUB1 bound to human UBC13== |
- | + | <StructureSection load='4dhi' size='340' side='right'caption='[[4dhi]], [[Resolution|resolution]] 1.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4dhi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DHI FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
- | --> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhi OCA], [https://pdbe.org/4dhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dhi RCSB], [https://www.ebi.ac.uk/pdbsum/4dhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhi ProSAT]</span></td></tr> |
- | + | </table> | |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/OTUBL_CAEEL OTUBL_CAEEL] Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin.<ref>PMID:19211026</ref> | ||
- | == | + | ==See Also== |
- | + | *[[Thioesterase 3D structures|Thioesterase 3D structures]] | |
- | + | *[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]] | |
- | + | == References == | |
- | + | <references/> | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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- | == | + | |
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[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Wang | + | [[Category: Wang T]] |
- | [[Category: Wiener | + | [[Category: Wiener R]] |
- | [[Category: Wolberger | + | [[Category: Wolberger C]] |
- | [[Category: Zhang | + | [[Category: Zhang X]] |
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Current revision
Structure of C. elegans OTUB1 bound to human UBC13
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