4e11
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of kynurenine formamidase from Drosophila melanogaster== | |
| - | + | <StructureSection load='4e11' size='340' side='right'caption='[[4e11]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4e11]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E11 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e11 OCA], [https://pdbe.org/4e11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e11 RCSB], [https://www.ebi.ac.uk/pdbsum/4e11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e11 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KFA_DROME KFA_DROME] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Han Q]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Robinson H]] | ||
Current revision
Crystal structure of kynurenine formamidase from Drosophila melanogaster
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