3ay5

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[[Image:3ay5.jpg|left|200px]]
 
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==Crystal structure of HHM (human homologue of murine maternal Id-like molecule)==
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The line below this paragraph, containing "STRUCTURE_3ay5", creates the "Structure Box" on the page.
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<StructureSection load='3ay5' size='340' side='right'caption='[[3ay5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ay5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AY5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ay5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ay5 OCA], [https://pdbe.org/3ay5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ay5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ay5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ay5 ProSAT]</span></td></tr>
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{{STRUCTURE_3ay5| PDB=3ay5 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of HHM (human homologue of murine maternal Id-like molecule)===
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[https://www.uniprot.org/uniprot/CCDB1_HUMAN CCDB1_HUMAN] May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.<ref>PMID:10801854</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3ay5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AY5 OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ishitani, R.]]
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[[Category: Large Structures]]
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[[Category: Nureki, O.]]
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[[Category: Ishitani R]]
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[[Category: Seto, A.]]
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[[Category: Nureki O]]
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[[Category: Cell cycle]]
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[[Category: Seto A]]
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[[Category: Dominant-negative helix-loop-helix transcriptional regulator]]
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Current revision

Crystal structure of HHM (human homologue of murine maternal Id-like molecule)

PDB ID 3ay5

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OCA

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