3lnr

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[[Image:3lnr.png|left|200px]]
 
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==Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2==
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The line below this paragraph, containing "STRUCTURE_3lnr", creates the "Structure Box" on the page.
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<StructureSection load='3lnr' size='340' side='right'caption='[[3lnr]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lnr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LNR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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{{STRUCTURE_3lnr| PDB=3lnr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lnr OCA], [https://pdbe.org/3lnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lnr RCSB], [https://www.ebi.ac.uk/pdbsum/3lnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lnr ProSAT]</span></td></tr>
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</table>
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===Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2===
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== Function ==
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[https://www.uniprot.org/uniprot/MCPB_PSEAE MCPB_PSEAE] Chemoreceptor that plays a critical role in the virulence and pathogenesis of P.aeruginosa in a variety of hosts (PubMed:31511598). Probably acts through oxygen sensing (PubMed:31511598, PubMed:28167524, PubMed:34383467). Uses a heme-based sensor (PubMed:21255112, PubMed:22622145). Could be involved in chemotaxis (PubMed:12142407, PubMed:14987771). When expressed in E.coli, is able to sense and mediate repellent responses to oxygen, carbon monoxide and nitric oxide (PubMed:21255112).<ref>PMID:12142407</ref> <ref>PMID:14987771</ref> <ref>PMID:21255112</ref> <ref>PMID:22622145</ref> <ref>PMID:28167524</ref> <ref>PMID:31511598</ref> <ref>PMID:34383467</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_20399181}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 20399181 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/3lnr_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_20399181}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3lnr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNR OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lnr ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:020399181</ref><references group="xtra"/>
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<references/>
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[[Category: Pseudomonas aeruginosa]]
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__TOC__
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[[Category: Airola, M V.]]
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</StructureSection>
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[[Category: Bilwes, A M.]]
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[[Category: Large Structures]]
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[[Category: Crane, B R.]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Hamp domain]]
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[[Category: Airola MV]]
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[[Category: Poly-hamp domain]]
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[[Category: Bilwes AM]]
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[[Category: Signaling protein]]
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[[Category: Crane BR]]

Current revision

Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2

PDB ID 3lnr

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