3o1d

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[[Image:3o1d.png|left|200px]]
 
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==Structure-function study of Gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.==
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The line below this paragraph, containing "STRUCTURE_3o1d", creates the "Structure Box" on the page.
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<StructureSection load='3o1d' size='340' side='right'caption='[[3o1d]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3o1d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O1D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4007&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G72:(1R,3R,7E,17BETA)-17-[(1S)-6,6,6-TRIFLUORO-5-HYDROXY-1-(4-HYDROXY-4-METHYLPENTYL)-5-(TRIFLUOROMETHYL)HEX-3-YN-1-YL]-9,10-SECOESTRA-5,7-DIENE-1,3-DIOL'>G72</scene></td></tr>
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{{STRUCTURE_3o1d| PDB=3o1d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o1d OCA], [https://pdbe.org/3o1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o1d RCSB], [https://www.ebi.ac.uk/pdbsum/3o1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o1d ProSAT]</span></td></tr>
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</table>
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===Structure-function study of Gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.===
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== Function ==
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[https://www.uniprot.org/uniprot/VDRA_DANRE VDRA_DANRE] Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Plays a central role in calcium homeostasis.<ref>PMID:17218092</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22180837 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22180837}}
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==About this Structure==
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[[3o1d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O1D OCA].
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==Reference==
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<ref group="xtra">PMID:022180837</ref><references group="xtra"/>
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[[Category: Danio rerio]]
[[Category: Danio rerio]]
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[[Category: Huet, T.]]
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[[Category: Homo sapiens]]
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[[Category: Moras, D.]]
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[[Category: Large Structures]]
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[[Category: Rochel, N.]]
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[[Category: Huet T]]
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[[Category: Nucleus]]
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[[Category: Moras D]]
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[[Category: Transcription factor]]
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[[Category: Rochel N]]
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[[Category: Transcription-transcription activator complex]]
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[[Category: Vitamin d]]
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Current revision

Structure-function study of Gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.

PDB ID 3o1d

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OCA

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