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3ifk

From Proteopedia

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[[Image:3ifk.png|left|200px]]
 
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==Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90==
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The line below this paragraph, containing "STRUCTURE_3ifk", creates the "Structure Box" on the page.
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<StructureSection load='3ifk' size='340' side='right'caption='[[3ifk]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ifk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_3ifk| PDB=3ifk | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ifk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ifk OCA], [https://pdbe.org/3ifk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ifk RCSB], [https://www.ebi.ac.uk/pdbsum/3ifk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ifk ProSAT]</span></td></tr>
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</table>
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===Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90===
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== Function ==
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[https://www.uniprot.org/uniprot/CALM1_RAT CALM1_RAT] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_21609874}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 21609874 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/3ifk_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_21609874}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3ifk]] is a 2 chain structure of [[Calmodulin]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFK OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ifk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Calmodulin]]
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*[[Calmodulin 3D structures|Calmodulin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021609874</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Newman, R A.]]
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[[Category: Newman RA]]
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[[Category: Shea, M A.]]
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[[Category: Shea MA]]
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[[Category: Witt, T J.]]
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[[Category: Witt TJ]]
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[[Category: Calmodulin]]
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[[Category: Ef hand motif]]
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[[Category: Isopeptide bond]]
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[[Category: Metal binding protein]]
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[[Category: Methylation]]
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[[Category: N-domain]]
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[[Category: N-terminal domain]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Residues 1-90]]
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Current revision

Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90

PDB ID 3ifk

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