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4e3i
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4e3i is ON HOLD Authors: Eidam, O., Shoichet, B.K. Description: Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benz...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benzyl sulfonamide boronic acid inhibitor== | |
| + | <StructureSection load='4e3i' size='340' side='right'caption='[[4e3i]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4e3i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E3I FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0N3:3-({[(DIHYDROXYBORANYL)METHYL]SULFAMOYL}METHYL)BENZOIC+ACID'>0N3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e3i OCA], [https://pdbe.org/4e3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e3i RCSB], [https://www.ebi.ac.uk/pdbsum/4e3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e3i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Eidam O]] | ||
| + | [[Category: Shoichet BK]] | ||
Current revision
Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benzyl sulfonamide boronic acid inhibitor
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