2lle

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[[Image:2lle.jpg|left|200px]]
 
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==Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds==
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The line below this paragraph, containing "STRUCTURE_2lle", creates the "Structure Box" on the page.
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<StructureSection load='2lle' size='340' side='right'caption='[[2lle]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2lle]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lle OCA], [https://pdbe.org/2lle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lle RCSB], [https://www.ebi.ac.uk/pdbsum/2lle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lle ProSAT]</span></td></tr>
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{{STRUCTURE_2lle| PDB=2lle | SCENE= }}
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</table>
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== Function ==
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===Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds===
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[https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013][https://www.uniprot.org/uniprot/CHEY_THEMA CHEY_THEMA] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_22329686}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 22329686 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22329686}}
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==About this Structure==
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[[2lle]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLE OCA].
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==Reference==
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<ref group="xtra">PMID:022329686</ref><references group="xtra"/>
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Coles, M.]]
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[[Category: Coles M]]
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[[Category: Eisenbeis, S.]]
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[[Category: Eisenbeis S]]
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[[Category: Hocker, B.]]
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[[Category: Hocker B]]
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[[Category: Meiler, J.]]
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[[Category: Meiler J]]
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[[Category: Proffitt, W.]]
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[[Category: Proffitt W]]
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[[Category: Truffault, V.]]
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[[Category: Truffault V]]
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[[Category: Chimeric protein]]
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[[Category: Computationally designed protein]]
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[[Category: Lyase]]
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[[Category: Tim-barrel]]
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Current revision

Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds

PDB ID 2lle

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OCA

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