1kny

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[[Image:1kny.png|left|200px]]
 
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==KANAMYCIN NUCLEOTIDYLTRANSFERASE==
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The line below this paragraph, containing "STRUCTURE_1kny", creates the "Structure Box" on the page.
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<StructureSection load='1kny' size='340' side='right'caption='[[1kny]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kny]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. The February 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aminoglycoside Antibiotics'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_2 10.2210/rcsb_pdb/mom_2012_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KNY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1kny| PDB=1kny | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kny OCA], [https://pdbe.org/1kny PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kny RCSB], [https://www.ebi.ac.uk/pdbsum/1kny PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kny ProSAT]</span></td></tr>
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</table>
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===KANAMYCIN NUCLEOTIDYLTRANSFERASE===
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== Function ==
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[https://www.uniprot.org/uniprot/KANU_STAAU KANU_STAAU] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 7577914 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7577914}}
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==About this Structure==
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[[1kny]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. The February 2012 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aminoglycoside Antibiotics'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2012_2 10.2210/rcsb_pdb/mom_2012_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNY OCA].
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==Reference==
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<ref group="xtra">PMID:007577914</ref><references group="xtra"/>
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[[Category: Aminoglycoside Antibiotics]]
[[Category: Aminoglycoside Antibiotics]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Benning, M M.]]
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[[Category: Benning MM]]
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[[Category: Holden, H M.]]
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[[Category: Holden HM]]
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[[Category: Pedersen, L C.]]
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[[Category: Pedersen LC]]
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[[Category: Antibiotic resistance]]
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[[Category: Transferase]]
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Current revision

KANAMYCIN NUCLEOTIDYLTRANSFERASE

PDB ID 1kny

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