3rko

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[[Image:3rko.png|left|200px]]
 
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==Crystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolution==
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The line below this paragraph, containing "STRUCTURE_3rko", creates the "Structure Box" on the page.
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<StructureSection load='3rko' size='340' side='right'caption='[[3rko]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rko]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. The December 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Complex I'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_12 10.2210/rcsb_pdb/mom_2011_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RKO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA7:7-CYCLOHEXYLHEPTYL+4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE'>CA7</scene>, <scene name='pdbligand=LFA:EICOSANE'>LFA</scene></td></tr>
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{{STRUCTURE_3rko| PDB=3rko | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rko OCA], [https://pdbe.org/3rko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rko RCSB], [https://www.ebi.ac.uk/pdbsum/3rko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rko ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NUOK_ECOBD NUOK_ECOBD] NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.[HAMAP-Rule:MF_01456]
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===Crystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolution===
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==See Also==
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*[[NADH-quinone oxidoreductase|NADH-quinone oxidoreductase]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21822288 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21822288}}
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==About this Structure==
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[[3rko]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The December 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Complex I'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_12 10.2210/rcsb_pdb/mom_2011_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKO OCA].
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==Reference==
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<ref group="xtra">PMID:021822288</ref><references group="xtra"/>
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[[Category: Complex I]]
[[Category: Complex I]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Efremov, R G.]]
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[[Category: Efremov RG]]
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[[Category: Sazanov, L A.]]
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[[Category: Sazanov LA]]
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[[Category: Complex i]]
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[[Category: Cytoplasmic membrane]]
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[[Category: Membrane protein]]
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[[Category: Nadh]]
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[[Category: Oxidoreductase]]
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[[Category: Proton pump]]
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[[Category: Ubiquinone]]
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Current revision

Crystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolution

PDB ID 3rko

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