3d7j

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[[Image:3d7j.png|left|200px]]
 
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==SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor==
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The line below this paragraph, containing "STRUCTURE_3d7j", creates the "Structure Box" on the page.
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<StructureSection load='3d7j' size='340' side='right'caption='[[3d7j]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d7j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D7J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_3d7j| PDB=3d7j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d7j OCA], [https://pdbe.org/3d7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d7j RCSB], [https://www.ebi.ac.uk/pdbsum/3d7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d7j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O86696_STRCO O86696_STRCO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d7/3d7j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d7j ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The X-ray crystal structure of the 6-pyruvoyltetrahydropterin synthase (PTPS) homolog from Streptomyces coelicolor, SCO 6650, was solved at 1.5 A resolution. SCO 6650 forms a hexameric T-fold that closely resembles other PTPS proteins. The biological activity of SCO 6650 is unknown, but it lacks both a required active-site zinc metal ion and the essential catalytic triad and does not catalyze the PTPS reaction. However, SCO 6650 maintains active-site residues consistent with binding a pterin-like substrate.
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===SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor===
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Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor.,Spoonamore JE, Roberts SA, Heroux A, Bandarian V Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):875-9., Epub 2008 Sep 30. PMID:18931427<ref>PMID:18931427</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18931427}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3d7j" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18931427 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_18931427}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3d7j]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D7J OCA].
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==Reference==
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<ref group="xtra">PMID:018931427</ref><references group="xtra"/>
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[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Bandarian, V.]]
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[[Category: Bandarian V]]
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[[Category: Heroux, A.]]
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[[Category: Heroux A]]
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[[Category: Roberts, S A.]]
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[[Category: Roberts SA]]
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[[Category: Spoonamore, J E.]]
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[[Category: Spoonamore JE]]
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[[Category: T-fold]]
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[[Category: Unknown function]]
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Current revision

SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor

PDB ID 3d7j

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