2ld5
From Proteopedia
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- | [[Image:2ld5.png|left|200px]] | ||
- | < | + | ==Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA== |
- | + | <StructureSection load='2ld5' size='340' side='right'caption='[[2ld5]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2ld5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LD5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ld5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ld5 OCA], [https://pdbe.org/2ld5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ld5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ld5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ld5 ProSAT]</span></td></tr> | |
- | + | </table> | |
+ | == Disease == | ||
+ | [https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Defects in Hoxa13 are the cause of hypodactyly (Hd), a condition characterized by profound deficiency of digital arch structures. | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity). | ||
- | == | + | ==See Also== |
- | + | *[[Hox protein|Hox protein]] | |
- | + | __TOC__ | |
- | < | + | </StructureSection> |
- | + | [[Category: Large Structures]] | |
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- | [[ | + | |
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[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
- | [[Category: Zhang | + | [[Category: Zhang Y]] |
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Current revision
Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA
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