4a0e

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[[Image:4a0e.png|left|200px]]
 
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==Crystal structure of the cytoplasmic N-terminal domain of Yersinia pestis YscD==
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The line below this paragraph, containing "STRUCTURE_4a0e", creates the "Structure Box" on the page.
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<StructureSection load='4a0e' size='340' side='right'caption='[[4a0e]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4a0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A0E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.042&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0e OCA], [https://pdbe.org/4a0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a0e RCSB], [https://www.ebi.ac.uk/pdbsum/4a0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0e ProSAT]</span></td></tr>
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{{STRUCTURE_4a0e| PDB=4a0e | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q56975_YERPE Q56975_YERPE]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The Yersinia pestis YscD protein is an essential component of the type III secretion system. YscD consists of an N-terminal cytoplasmic domain (residues 1-121), a transmembrane linker (122-142) and a large periplasmic domain (143-419). Both the cytoplasmic and the periplasmic domains are required for the assembly of the type III secretion system. Here, the structure of the YscD cytoplasmic domain solved by SAD phasing is presented. Although the three-dimensional structure is similar to those of forkhead-associated (FHA) domains, comparison with the structures of canonical FHA domains revealed that the cytoplasmic domain of YscD lacks the conserved residues that are required for binding phosphothreonine and is therefore unlikely to function as a true FHA domain.
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===Crystal structure of the cytoplasmic N-terminal domain of Yersinia pestis YscD===
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Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system.,Lountos GT, Tropea JE, Waugh DS Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):201-9. Epub 2012 Feb 7. PMID:22349221<ref>PMID:22349221</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 4a0e" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 22349221 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22349221}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[4a0e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0E OCA].
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==Reference==
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<ref group="xtra">PMID:022349221</ref><references group="xtra"/>
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[[Category: Yersinia pestis]]
[[Category: Yersinia pestis]]
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[[Category: Lountos, G T.]]
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[[Category: Lountos GT]]
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[[Category: Tropea, J E.]]
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[[Category: Tropea JE]]
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[[Category: Waugh, D S.]]
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[[Category: Waugh DS]]
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[[Category: Sad phasing]]
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[[Category: Transport protein]]
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[[Category: Type iii secretion system]]
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Current revision

Crystal structure of the cytoplasmic N-terminal domain of Yersinia pestis YscD

PDB ID 4a0e

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