3rg2

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[[Image:3rg2.png|left|200px]]
 
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==Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis==
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The line below this paragraph, containing "STRUCTURE_3rg2", creates the "Structure Box" on the page.
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<StructureSection load='3rg2' size='340' side='right'caption='[[3rg2]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3rg2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RG2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene>, <scene name='pdbligand=SVS:5-DEOXY-5-({[2-(2-HYDROXYPHENYL)ETHYL]SULFONYL}AMINO)ADENOSINE'>SVS</scene></td></tr>
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{{STRUCTURE_3rg2| PDB=3rg2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rg2 OCA], [https://pdbe.org/3rg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rg2 RCSB], [https://www.ebi.ac.uk/pdbsum/3rg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rg2 ProSAT]</span></td></tr>
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</table>
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===Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis===
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== Function ==
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[https://www.uniprot.org/uniprot/ENTB_ECOLI ENTB_ECOLI] Required for production of 2,3-DHB. Also serves as an aryl carrier protein and plays a role in enterobactin assembly.[https://www.uniprot.org/uniprot/ENTE_ECOLI ENTE_ECOLI] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine.
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22365602 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22365602}}
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==About this Structure==
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[[3rg2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG2 OCA].
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==Reference==
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<ref group="xtra">PMID:022365602</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Gulick, A M.]]
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[[Category: Large Structures]]
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[[Category: Sundlov, J A.]]
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[[Category: Gulick AM]]
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[[Category: 4'phosphopantetheinylation 4'pp cofactor]]
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[[Category: Sundlov JA]]
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[[Category: Adenylate-forming enzyme]]
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[[Category: Anl superfamily]]
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[[Category: Ligase]]
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[[Category: Non-ribosomal peptide synthetase carrier protein function]]
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[[Category: Nrps adenylation domain acyl carrier protein]]
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Current revision

Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis

PDB ID 3rg2

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OCA

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