3s4w

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[[Image:3s4w.png|left|200px]]
 
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==Structure of the FANCI-FANCD2 complex==
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The line below this paragraph, containing "STRUCTURE_3s4w", creates the "Structure Box" on the page.
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<StructureSection load='3s4w' size='340' side='right'caption='[[3s4w]], [[Resolution|resolution]] 3.41&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s4w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S4W FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.408&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s4w OCA], [https://pdbe.org/3s4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s4w RCSB], [https://www.ebi.ac.uk/pdbsum/3s4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s4w ProSAT]</span></td></tr>
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{{STRUCTURE_3s4w| PDB=3s4w | SCENE= }}
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</table>
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== Function ==
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===Structure of the FANCI-FANCD2 complex===
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[https://www.uniprot.org/uniprot/FANCI_MOUSE FANCI_MOUSE] Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_21764741}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21764741 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21764741}}
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==About this Structure==
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[[3s4w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S4W OCA].
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==Reference==
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<ref group="xtra">PMID:021764741</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Pavletich, N P.]]
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[[Category: Pavletich NP]]
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[[Category: Dna binding protein]]
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[[Category: Dna repair]]
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Current revision

Structure of the FANCI-FANCD2 complex

PDB ID 3s4w

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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